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progesterone + dydrogesterone
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Oral, Vaginal, Intramuscular
01
Overview
A combination therapy using both progesterone and dydrogesterone, two progestogenic agents. Progesterone is a natural hormone, while dydrogesterone is a synthetic progestogen with a molecular structure similar to natural progesterone but with improved oral bioavailability and metabolic stability. This combination has been studied particularly for luteal phase support in assisted reproduction techniques and for the treatment of threatened miscarriage due to corpus luteum insufficiency. Studies suggest that the combination may provide higher clinical pregnancy rates and lower miscarriage rates compared to progesterone alone.
02
Targets
MR (Mineralocorticoid receptor)PR (Progesterone receptor)
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