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Program 3 (Sauvie Inc.)

Development stage
Preclinical
Lead developer
Sauvie
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
01

Overview

Program 3 is a preclinical-stage multi-specific antibody candidate being developed by Sauvie using its proprietary CAM-V™ (Constant domain of Antibody Mimicry and Variation) platform. The therapeutic is designed to engage CD16a (FcγRIIIa), an activating receptor found on immune effector cells such as Natural Killer (NK) cells and macrophages, to trigger immune activation and target lysis. While the primary immune-engaging target is CD16a, the second target (Target 3) remains undisclosed by the company. The program is currently in the mid-discovery phase of preclinical development, intended for the treatment of cancer.

Other names
Program 3-Sauvie-CD16a-Target 3 (undisclosed)-CAM-V antibody
02

Targets

FCGR3A (Low affinity immunoglobulin gamma Fc region receptor III-A)

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