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Drug intelligence / Profile preview
propofol (Daewon Pharm)
- Development stage
- Phase 1
- Lead developer
- Daewon Pharm
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
Freefol-MCT is a microemulsion formulation of the intravenous anesthetic propofol, developed by Daewon Pharm. It is characterized by the use of a medium-chain triglyceride (MCT) and long-chain triglyceride (LCT) lipid vehicle, which distinguishes it from traditional LCT-only emulsions. This microemulsion technology is intended to enhance the physicochemical stability of the drug and reduce the incidence of injection-site pain, a frequent adverse effect associated with standard propofol formulations. Freefol-MCT is approved for the induction and maintenance of general anesthesia, as well as for the sedation of ventilated patients in intensive care and for monitored anesthesia care.
- Brand names
- Freefol-MCT
- Other names
- Freefol-MCT Inj.propofol microemulsion
02
Targets
CaV (Voltage-gated calcium channel protein complex)Glycine receptorNicotinic Acetylcholine ReceptorKCNQ1 (Potassium voltage-gated channel subfamily KQT member 1)NaV (Voltage-gated sodium channels)GABRA1 (Gamma-aminobutyric acid type A receptor alpha 1 subunit)
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