Drug intelligence / Profile preview

propranolol + nandrolone decanoate

Development stage
Unknown
Lead developer
King Edward Medical University
Modality
Small Molecules
Administration
Oral, Intramuscular
01

Overview

Propranolol + nandrolone decanoate is a combination therapy being investigated by King Edward Medical University for the management of pediatric patients with severe burns (20-40% total body surface area). Propranolol is a non-selective beta-adrenergic blocker that mitigates the systemic hypermetabolic and catabolic responses triggered by the massive release of catecholamines following burn trauma. Nandrolone decanoate is an anabolic steroid that promotes protein synthesis and increases bone mineral density. The combination is specifically designed to counteract the severe catabolic state and growth arrest commonly observed in children recovering from major burn injuries, thereby improving long-term clinical outcomes.

Other names
Propranolol and Nandrolone DecanoatePropranolol and Nandrolone
02

Targets

ADRB2 (β2)ADRB1 (β1)

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