Drug intelligence / Profile preview

pyrethrins + piperonyl butoxide (Johnson & Johnson)

Development stage
Unknown
Lead developer
Ego Pharmaceuticals
Modality
Small Molecules
Administration
Topical
01

Overview

Banlice Mousse is an over-the-counter topical insecticide used for the treatment of head lice (pediculosis capitis). It is a combination product containing pyrethrins, a natural insecticide derived from chrysanthemum flowers, and piperonyl butoxide, a synergist that inhibits the detoxification enzymes of the lice, thereby enhancing the efficacy of the pyrethrins. The product is formulated as a pressurized aerosol mousse, which is applied to dry hair to kill both live lice and their eggs (nits) by targeting the insect's nervous system. It is a market-leading treatment in Australia and has been used as a clinical comparator in trials for newer pediculicides.

Brand names
Banlice Mousse
Other names
Banlice
02

Targets

Cyp (Cyclophilin family)NaV (Voltage-gated sodium channels)

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