Drug intelligence / Profile preview

Qigui Yishen Prescription (First Affiliated Hospital of Soochow University)

Development stage
Unknown
Lead developer
First Affiliated Hospital of Soochow University
Administration
Oral
01

Overview

Qigui Yishen Prescription is a Traditional Chinese Medicine (TCM) herbal formula developed by the First Affiliated Hospital of Soochow University. It is primarily investigated for its potential to mitigate and delay the progression of acute and chronic kidney diseases, particularly those induced by platinum-based chemotherapy agents such as cisplatin. The prescription typically contains *Astragalus membranaceus* (Huangqi) and *Angelica sinensis* (Danggui), which are traditionally used in TCM to tonify Qi and enrich blood while specifically targeting kidney health. In clinical settings, it is used in combination with Western medical protocols to provide a synergistic effect in preserving renal function, reducing nephrotoxicity, and managing chronic renal failure.

Other names
Qigui Yishen DecoctionQigui Yishen FormulaQi Gui Yi Shen Fang
02

Targets

COL1A1 (Collagen type I alpha 1 chain)PAI-1 (Plasminogen activator inhibitor type 1)THBD (Thrombomodulin)TGFB1 (Transforming growth factor Beta-1 proprotein)

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