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Qing'ao Granules is a Traditional Chinese Medicine (TCM) formulation developed as an in-hospital preparation by the Liangshan Prefecture Hospital of Traditional Chinese Medicine. It is primarily indicated for the treatment of chronic hepatitis B (CHB). The granules are used as an adjunctive therapy to enhance the efficacy of standard antiviral regimens, such as peginterferon α-2b and nucleos(t)ide analogues (NAs), particularly in patients who have achieved HBV DNA negativity but still carry low levels of HBsAg. The clinical objective of adding Qing'ao Granules is to promote HBsAg seroconversion and achieve a functional cure. As a botanical-based therapy, its pharmacological profile likely involves the modulation of the host immune response and protection of hepatic function.
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