Qishen'gubiao Granule

Qishen'gubiao Granule is a traditional Chinese medicine (TCM) preparation composed of nine herbs. It has been widely used for the prevention and treatment of coronavirus disease 2019 (COVID-19) and chronic heart failure (CHF). The granules are prepared by water extraction followed by alcohol sedimentation, resulting in a botanical drug formulation. Clinical studies have shown that Qishen'gubiao Granules can improve cardiac function in CHF patients by reducing N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels, improving New York Heart Association functional classification, increasing 6-minute walking distance, and enhancing quality of life measures. For COVID-19, network pharmacology and molecular docking studies suggest that active compounds such as quercetin, apigenin, scutellarein, luteolin, and naringenin target key proteins including angiotensin-converting enzyme 2 and 3-chymotrypsin-like protease to modulate immune and inflammatory pathways. The product is manufactured as granules with lactose excipient for oral administration.

Brand names

Qishen Gubiao granulesQishen Gubiao Keli芪参固表颗粒

Other names

Qishen Gubiao granulesQSG