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quadrivalent split-virion influenza vaccine (Shenzhen Kangtai Biological Products)

Development stage
Preclinical
Lead developer
Shenzhen Kangtai Biological Products
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

The 4-valent influenza vaccine (split) is a quadrivalent split-virion vaccine candidate being developed by Shenzhen Kangtai Biological Products (Shenzhen Kangde) for the prevention of seasonal influenza. As a quadrivalent vaccine, it is designed to provide broader protection than traditional trivalent vaccines by including antigens from four different influenza virus strains: two influenza A subtypes (typically H1N1 and H3N2) and two influenza B lineages (typically Victoria and Yamagata). The split-virion technology involves disrupting the virus with detergents to expose internal and surface antigens, which generally results in a vaccine that is highly immunogenic while maintaining a favorable safety profile. The candidate is currently in the preclinical/R&D stage of development.

Other names
4-valent influenza vaccine4-Valent Influenza Vaccine (split)Quadrivalent Influenza VaccineQuadrivalent split-virion influenza vaccine
02

Targets

HA (Influenza virus hemagglutinin (quadrivalent))Neuraminidase

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