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Antirabique tissulaire lyophilisé is an inactivated rabies vaccine produced by the Pasteur Institute of Algeria using the Fuenzalida-Palacios method. The vaccine is derived from the brain tissue of suckling mice, which is then inactivated and lyophilized for stability. It is indicated for both pre-exposure and post-exposure prophylaxis against rabies in humans. While cell-culture-derived vaccines are the current international standard, this tissue-derived formulation remains a critical part of the local production portfolio in Algeria to ensure the availability of rabies prevention measures. The vaccine works by inducing the production of neutralizing antibodies against the rabies virus, providing active immunity to the recipient.
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