Drug intelligence / Profile preview

rabies vaccine (human diploid cell) (Ab&B Bio-tech)

Development stage
Unknown
Lead developer
Ab&B Bio-tech Co., Ltd.
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Ab&B Bio-tech's human diploid cell rabies vaccine is a freeze-dried, inactivated biologic developed for both pre-exposure and post-exposure prophylaxis against rabies. Cultivated using human diploid cells—a substrate known for high safety and low adverse reaction rates compared to animal-derived cell lines—this vaccine is designed to stimulate a robust immune response against the rabies virus. It has entered Phase III clinical trials to evaluate its safety and immunogenicity across various immunization schedules, including the five-dose Essen regimen, the four-dose Zagreb (2-1-1) regimen, and simplified four-dose schedules. The manufacturing process emphasizes high purification and potency, positioning it as a next-generation alternative to traditional Vero cell-based rabies vaccines.

Other names
Rabies Vaccine (Human Diploid Cell) for Human Use, Freeze-driedJS-rabiesfreeze-dried rabies vaccine (human diploid cell)

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