ramipril + amlodipine + atorvastatin

A fixed-dose combination of three pharmaceutical agents: ramipril, an angiotensin-converting enzyme (ACE) inhibitor; amlodipine, a calcium channel blocker; and atorvastatin, a statin. This combination is primarily used to treat hypertension (high blood pressure) and to reduce cardiovascular risk in patients with coexisting dyslipidemia. Ramipril lowers blood pressure by inhibiting the conversion of angiotensin I to angiotensin II, leading to vasodilation. Amlodipine relaxes vascular smooth muscle by blocking L-type calcium channels, further reducing blood pressure. Atorvastatin inhibits HMG-CoA reductase in the liver, lowering LDL cholesterol and triglycerides while raising HDL cholesterol. Together, these agents address both elevated blood pressure and abnormal lipid profiles to reduce overall cardiovascular risk[1][5].

Brand names

No widely established single brand name for the triple combination; individual components have brands such as Norvasc (amlodipine), Lipitor (atorvastatin), and Altace (ramipril)

Other names

amlodipine + atorvastatin + ramiprilamlodipine/atorvastatin/ramipril