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Rebecsinib (Univ. of California San Diego)
- Development stage
- Preclinical
- Lead developer
- University of California, San Diego
- Modality
- Small Molecules
01
Overview
Rebecsinib (Univ. of California San Diego): sourced facts only. name: "Rebecsinib is a small-molecule inhibitor designed to block splicing-mediated activation of ADAR1 (adenosine deaminase acting on RNA 1)." [DOI:10.1158/1538-7445.am2026-7105]; target: "Rebecsinib is a small-molecule inhibitor designed to block splicing-mediated activation of ADAR1 (adenosine deaminase acting on RNA 1)." [DOI:10.1158/1538-7445.am2026-7105]; developer: "University of California San Diego, La Jolla, CA." [DOI:10.1158/1538-7445.am2026-7105]; modality: "Rebecsinib is a small-molecule inhibitor designed to block splicing-mediated activation of ADAR1 (adenosine deaminase acting on RNA 1)." [DOI:10.1158/1538-7445.am2026-7105]; stage: "Rebecsinib selectively reduces CD44+ and ADAR1+ TNBC cell populations and inhibits tumor progression in humanized preclinical models." [DOI:10.1158/1538-7445.am2026-7105]
02
Targets
ADAR (Adenosine deaminases acting on RNA (ADAR) family)
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