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recombinant hepatitis B vaccine (Govind Ballabh Pant Hospital)

Development stage
Unknown
Lead developer
Govind Ballabh Pant Hospital
Modality
Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Recombinant hepatitis B vaccine is a prophylactic agent used to prevent infection by the hepatitis B virus (HBV). It is composed of purified hepatitis B surface antigen (HBsAg) produced through recombinant DNA technology, typically expressed in yeast (*Saccharomyces cerevisiae*) or mammalian cell lines. The vaccine works by inducing the production of specific neutralizing antibodies (anti-HBs) in the recipient, providing active immunity against the virus. In clinical research conducted by Govind Ballabh Pant Hospital, this vaccine has been evaluated for its efficacy in preventing perinatal transmission of HBV from HBsAg-positive mothers to their newborns, comparing regimens of the vaccine alone against the combination of the vaccine with hepatitis B immune globulin (HBIG).

Other names
hepatitis B vaccineHBV vaccinerecombinant HBsAg vaccineHBsAg vaccine
02

Targets

HBsAg (Hepatitis B surface antigen)

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