Drug intelligence / Profile preview

recombinant human papillomavirus bivalent (types 16 and 18) vaccine

Development stage
Phase 3
Lead developer
GSK
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

This recombinant human papillomavirus bivalent vaccine targets types 16 and 18 of the Human Papillomavirus. It is designed to evaluate its safety and immunogenicity in healthy females aged 9-45 years. The vaccine is administered via a three-dose schedule (0, 2, 6 months) and aims to induce an immune response, specifically neutralizing antibodies, against HPV types 16 and 18. The recombinant proteins are produced in yeast.

Brand names
Cervarix
Other names
HPV-16/18 L1/AS04 vaccinebivalent HPV vaccineHPV 16/18 vaccinehuman papillomavirus bivalent (types 16 and 18) vaccine, recombinant
02

Targets

HPV16 (Human papillomavirus type 16)HPV18 L1TLR4 (Toll-like receptor 4)

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