recombinant type III humanized collagen + type XVII humanized collagen

This therapeutic combination consists of recombinant humanized type III collagen (rhCol III) and recombinant humanized type XVII collagen (rhCol XVII). Type III collagen is a major structural component of the extracellular matrix, particularly in the skin, where it plays a critical role in wound healing, tissue elasticity, and the modulation of inflammatory responses. Type XVII collagen is a specialized transmembrane protein (COL17A1) that serves as a key component of hemidesmosomes, which anchor keratinocytes to the basement membrane. In the context of rosacea, this combination is designed to repair the compromised skin barrier and stabilize the dermal-epidermal junction (DEJ). By providing these structural proteins, the treatment aims to reduce chronic inflammation, alleviate persistent erythema, and improve the overall integrity of the skin. The development and clinical evaluation of this specific combination for rosacea are primarily associated with The First Affiliated Hospital of Army Medical University.

Other names

rhCol III + rhCol XVIIrecombinant humanized type III collagen and type XVII collagen combination