Drug intelligence / Profile preview

Recombinant Zoster Vaccine (CHO Cell)

Development stage
Unknown
Lead developer
MAXVAX Biotechnology
Modality
Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Recombinant Zoster Vaccine (CHO Cell) is an investigational recombinant subunit vaccine developed by MAXVAX Biotechnology for the prevention of herpes zoster (shingles) in adults aged 40 years and older. The vaccine utilizes the varicella-zoster virus (VZV) glycoprotein E (gE) as its primary antigen, which is expressed in Chinese Hamster Ovary (CHO) cells. It is formulated with the proprietary MA105 adjuvant system to enhance the immune response. Administered via intramuscular injection in a two-dose schedule (0 and 2 months), the vaccine is currently in Phase III clinical trials in China to evaluate its efficacy, safety, immunogenicity, and lot-to-lot consistency of commercial-scale production batches.

Other names
Recombinant Herpes Zoster Vaccine (CHO Cell)MAXVAX Herpes Zoster Vaccine
02

Targets

gE (VZV glycoprotein E)

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