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red ginseng + gamma cyclodextrin
- Development stage
- Unknown
- Lead developer
- Scientific Center of Drug and Medical Technologies Expertise
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Red ginseng + gamma cyclodextrin is a specialized bioavailability-enhanced formulation of red ginseng extract (*Panax ginseng*) complexed with gamma-cyclodextrin ($\gamma$-CD). Gamma-cyclodextrin acts as a molecular carrier, forming inclusion complexes with the hydrophobic ginsenosides (such as Rg3, Rb1, and Compound K) found in red ginseng. This complexation significantly improves the solubility and intestinal absorption of these active compounds, which are otherwise poorly absorbed due to their large molecular size and low water solubility. The formulation is primarily marketed as a nutraceutical for its adaptogenic properties, including cognitive support, fatigue reduction, and immune system modulation. The technology for this specific complex was notably developed using Wacker Chemie's CAVAMAX W8 cyclodextrin platform.
- Brand names
- Ginseng G3
- Other names
- gamma-cyclodextrin complexed red ginsengCAVAMAX W8 red ginseng complexGinseng G3 complex
02
Targets
TNFA (Tumor necrosis factor alpha (soluble))GABRA1 (Gamma-aminobutyric acid type A receptor alpha 1 subunit)GR (Glucocorticoid receptor)
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