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Red raspberry + fructooligosaccharide is a dietary supplement combination consisting of red raspberry (Rubus idaeus L.) and fructooligosaccharides (FOS). Red raspberries are rich in bioactive polyphenols, including anthocyanins and ellagitannins, while FOS serves as a prebiotic fiber. This combination has been investigated in randomized crossover clinical trials for its potential to improve metabolic health in adults with prediabetes and insulin resistance. Research indicates that the intervention can enhance beta-cell function and insulin secretion while modulating the gut microbiota, specifically increasing the abundance of beneficial bacteria such as Bifidobacterium species. The clinical investigation of this nutritional intervention has been supported by the National Processed Raspberry Council.
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