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red yeast rice + phytosterol esters + lycopene

Development stage
Unknown
Lead developer
H&H Group
Modality
Small Molecules
Administration
Oral
01

Overview

This is a combination dietary supplement containing three active ingredients—red yeast rice, phytosterol esters, and lycopene—formulated to support cardiovascular health, particularly for cholesterol management. - **Red yeast rice** is produced by fermenting white rice with the Monascus purpureus fungus. It contains monacolin K, which has the same chemical structure as lovastatin and can lower blood cholesterol by inhibiting HMG-CoA reductase[1][3]. - **Phytosterol esters** are plant-derived compounds structurally similar to cholesterol; they reduce intestinal absorption of dietary cholesterol, thereby lowering LDL ("bad") cholesterol levels[3][6]. - **Lycopene** is a carotenoid antioxidant found in tomatoes and other red fruits/vegetables; it may help reduce blood pressure and provide additional cardiovascular benefits through its antioxidant properties[3]. The combination aims to provide additive or synergistic effects on lipid lowering and cardiovascular protection. Clinical studies have evaluated combinations of these ingredients for their impact on lipid profiles in statin-intolerant patients or those seeking non-pharmaceutical alternatives[2][4][5].

02

Targets

HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)

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