Drug intelligence / Profile preview

relinqing granule + ciprofloxacin

Development stage
Unknown
Lead developer
The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine
Modality
Small Molecules
Administration
Oral
01

Overview

Relinqing Granule + ciprofloxacin is a combination therapy used for the treatment of chronic prostatitis, particularly chronic bacterial prostatitis and inflammatory chronic pelvic pain syndrome. Relinqing Granule is a Traditional Chinese Medicine (TCM) preparation derived from the herb *Polygonum capitatum*, which possesses anti-inflammatory, anti-infective, and diuretic properties. Ciprofloxacin is a second-generation fluoroquinolone antibiotic that exerts its bactericidal effect by inhibiting DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, and repair. The combination is designed to provide a synergistic effect where ciprofloxacin addresses the underlying bacterial infection while Relinqing Granule alleviates clinical symptoms such as urinary frequency, urgency, and pelvic pain by reducing inflammation and promoting diuresis. This therapeutic approach is widely studied and applied in China to improve cure rates and reduce the recurrence of prostatic inflammation.

Brand names
RelinqingCipro
Other names
Re-Lin-QingRelinqing Keli
02

Targets

DNA gyraseTopo IV (Bacterial Topoisomerase IV)

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