remifentanil + ciprofol

Remifentanil + ciprofol is a combination of two intravenous anesthetic agents used for sedation and anesthesia. Ciprofol is a novel 2,6-disubstituted phenol derivative that acts as a GABA-A receptor agonist, similar to propofol but with improved pharmacological properties. Remifentanil is an ultra-short-acting synthetic opioid analgesic. This combination provides effective sedation with more stable hemodynamics, less respiratory depression, and fewer adverse events compared to propofol-remifentanil combinations. The ciprofol-remifentanil combination has shown particular benefits in procedures such as bronchoscopy, gastrointestinal endoscopy, and general anesthesia, with reduced incidence of hypotension, hypoxemia, and injection pain.

Brand names

Cofol

Other names

cipofol + remifentanilHSK3486 + remifentanil