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remifentanil + clonidine
- Development stage
- Phase 2
- Lead developer
- Abbott
- Modality
- Small Molecules
- Administration
- Epidural, Paravertebral, Intravenous
01
Overview
A combination of remifentanil, a potent ultra short-acting synthetic opioid analgesic, and clonidine, an alpha-2 adrenergic agonist. This combination is used in anesthesia practice to enhance pain control, reduce anesthetic agent requirements, and decrease postoperative opioid needs. The synergistic effect of these medications provides effective analgesia with potentially fewer side effects than higher doses of either medication alone.
02
Targets
ADRA2A (α2A)MOR (Mu opioid receptor)
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