Drug intelligence / Profile preview

Repevax + Revaxis

Development stage
Unknown
Lead developer
Parent
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Repevax and Revaxis are booster vaccines developed by Sanofi Pasteur, designed to maintain protective immunity against several life-threatening bacterial and viral infections. Repevax is a quadrivalent vaccine (dTaP-IPV) containing reduced doses of diphtheria and tetanus toxoids, acellular pertussis antigens, and inactivated poliovirus; it is typically administered as a booster to children and adolescents. Revaxis is a trivalent vaccine (Td-IPV) containing reduced doses of diphtheria and tetanus toxoids along with inactivated poliovirus, but notably lacks the pertussis component; it is used for booster immunization in older children, adolescents, and adults. Both vaccines utilize reduced antigen content compared to primary series vaccines, making them suitable for booster doses to maintain long-term immunity. They contain toxoids and inactivated viruses adsorbed onto aluminum salts to enhance the immune response.

Brand names
Adacel-Polio
Other names
dTaP-IPVTd-IPV
02

Targets

PRN (Pertactin)FIM2/FIM3 (Fimbriae types 2 and 3)FHA (Filamentous hemagglutinin)TT (Tetanus toxoid)

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