Drug intelligence / Profile preview

resveratrol + myoinositol

Development stage
Unknown
Lead developer
S&R Farmaceutici
Modality
Small Molecules
Administration
Oral
01

Overview

**Resveratrol + myoinositol** is an oral nutraceutical combination studied as a co-administered therapy for polycystic ovary syndrome. Resveratrol is a stilbene polyphenol reported to activate sirtuin 1 and modulate metabolic, inflammatory, and endocrine pathways, while myoinositol is an insulin-sensitizing carbocyclic sugar involved in intracellular phosphatidylinositol signaling. In the completed randomized Phase 2 trial NCT04867252, twice-daily resveratrol 1000 mg plus myoinositol 1000 mg was evaluated in obese women with oligo-anovulatory polycystic ovary syndrome and was associated with improvements in menstrual regularity, endocrine measures including testosterone, adiponectin, anthropometric measures, and perceived stress. The combination is a research and nutraceutical regimen rather than a confirmed proprietary pharmaceutical product.

Other names
myo-inositol + resveratrolresveratrol + myo-inositolresveratrol + myoinositol
02

Targets

INSR (Insulin receptor)AR (Adrenergic receptors)

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