Drug intelligence / Profile preview

retinol + alpha-tocopherol

Development stage
Unknown
Lead developer
Minskintercaps
Modality
Small Molecules
Administration
Oral
01

Overview

Aevit is a combination pharmaceutical preparation containing high doses of Vitamin A (retinol palmitate) and Vitamin E (alpha-tocopherol acetate). It is widely utilized in Eastern Europe for the treatment of conditions associated with vitamin deficiencies and for diseases requiring enhanced antioxidant support. Vitamin A is critical for maintaining the integrity of epithelial tissues, supporting visual function, and regulating cell differentiation through its interaction with nuclear receptors. Vitamin E acts as a potent lipid-soluble antioxidant, protecting cellular membranes from lipid peroxidation and synergistically enhancing the biological activity of Vitamin A. The product is indicated for a variety of conditions, including atherosclerosis, peripheral vascular disorders, and dermatological diseases such as psoriasis and ichthyosis.

Brand names
Aevit
Other names
Vitamin A + Vitamin E
02

Targets

RARA (Retinoic acid receptor alpha)TTPA (Alpha-tocopherol transfer protein)RXRA (Retinoid X receptor alpha)

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