Drug intelligence / Profile preview

RHB-104 + interferon beta-1a

Development stage
Unknown
Lead developer
RedHill Biopharma
Modality
Recombinant Proteins and Enzymes, Small Molecules
Administration
Oral, Intramuscular, Subcutaneous
01

Overview

RHB-104 + interferon beta-1a is a combination therapy consisting of an oral antibiotic combination (RHB-104) and interferon beta-1a. RHB-104 contains three antibiotics (clarithromycin, clofazimine, and rifabutin) with potent intracellular, antimycobacterial and anti-inflammatory properties. This combination was studied as an add-on therapy for relapsing-remitting multiple sclerosis, based on the hypothesis that Mycobacterium avium subspecies paratuberculosis (MAP) infection may contribute to autoimmune diseases.

02

Targets

IFNAR (Immune system modulation via type I interferon receptor)

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