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rhEGF + sodium hyaluronate

Development stage
Unknown
Lead developer
Shanghai Haohai Biological Technology
Modality
Small Molecules, Recombinant Proteins and Enzymes, Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Ophthalmic
01

Overview

A combination ophthalmic formulation containing recombinant human epidermal growth factor (rhEGF) and sodium hyaluronate. This combination is primarily used as eye drops for the treatment of dry eye syndrome (xerophthalmia), particularly after cataract surgery. Sodium hyaluronate acts as a lubricant and moisture-retaining agent on the ocular surface, forming a protective film that enhances tear film stability and promotes corneal healing. Recombinant human EGF stimulates epithelial cell proliferation, accelerates corneal repair, improves microcirculation in the eye, and reduces inflammation by lowering levels of inflammatory cytokines such as IL-6 and TNF-α. Clinical studies have shown that this combination is more effective than sodium hyaluronate alone in improving symptoms of dry eye, promoting corneal healing, reducing ocular surface inflammation, and enhancing patients' quality of life[1][2][3][5].

Other names
recombinant human epidermal growth factor + sodium hyaluronaterhEGF + SHSH + rhEGF
02

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