rifampicin + SY-004

Rifampicin (also known as rifampin) is a broad-spectrum antibiotic belonging to the rifamycin class. It is primarily used to treat tuberculosis and eliminate *Neisseria meningitidis* from the nasopharynx in asymptomatic carriers. Its mechanism of action involves inhibition of bacterial DNA-dependent RNA polymerase, thereby suppressing RNA synthesis and bacterial replication[3][4][8]. SY-004 is an investigational small molecule described as a dual-acting full glucokinase activator under development for improving glucose control. It acts by activating glucokinase in both the liver and pancreas to enhance glucose metabolism and lower blood sugar levels[6]. The combination "rifampicin + SY-004" does not appear to be an established or marketed fixed-dose combination; rather it refers to co-administration or study use of both agents.

Brand names

RifadinRimactaneRifamateRifaterIsonarifRofact

Other names

rifampin