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rivaroxaban + acetylsalicylic acid + clopidogrel
- Development stage
- Preclinical
- Lead developer
- Bayer
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
A combination antithrombotic therapy consisting of rivaroxaban (a direct factor Xa inhibitor), acetylsalicylic acid (an antiplatelet agent that inhibits cyclooxygenase-1), and clopidogrel (a P2Y12 receptor antagonist). This triple therapy provides enhanced cardiovascular protection but significantly increases bleeding risk compared to single or dual therapy regimens.
- Brand names
- XareltoPlavix
- Other names
- triple therapytriple antithrombotic therapy
02
Targets
P2Y12 (Purinergic P2Y12 receptor)F10 (Factor Xa)PGHS-1 (Prostaglandin G/H Synthase 1)
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