RO4995819 + activated charcoal

RO4995819 + activated charcoal is a combination of an experimental small molecule psychiatric agent (RO4995819) and activated charcoal. RO4995819 is a psychoactive compound developed as a glycine transporter 1 (GlyT1) inhibitor for the treatment of schizophrenia and other central nervous system disorders. Activated charcoal is a gastric decontamination agent used to treat poisonings and overdoses due to its ability to adsorb (bind to) chemicals and drugs in the gastrointestinal tract, thereby reducing their absorption[5][4]. When administered together, activated charcoal may reduce the gastrointestinal absorption of RO4995819 by adsorbing it during transit, which can significantly alter RO4995819’s systemic exposure and pharmacokinetics[1][5].

Other names

RO4995819RO-4995819RO 4995819activated charcoal