rocuronium + sugammadex

Rocuronium + sugammadex is a combination used in anesthesia practice. Rocuronium is a non-depolarizing neuromuscular blocking agent (muscle relaxant) that induces temporary paralysis by competitively inhibiting acetylcholine at the neuromuscular junction, facilitating endotracheal intubation and providing skeletal muscle relaxation during surgery or mechanical ventilation. Sugammadex is a modified gamma-cyclodextrin that acts as a selective relaxant binding agent; it rapidly reverses the effects of steroidal non-depolarizing neuromuscular blockers like rocuronium by encapsulating and inactivating them, thereby restoring normal muscle function. This combination allows for rapid onset of paralysis with controlled and predictable reversal, improving safety and efficiency in surgical procedures[1][2][3][5][6].

Brand names

Esmeron + BridionSugagelan

Other names

Moderate Neuromuscular Blockade GroupControl Group (Yonsei University Thyroidectomy Study)