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Rosova+
- Development stage
- Preclinical
- Lead developer
- Indication Bioscience
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Rosova+ is an investigational oral fixed-dose combination small-molecule candidate from Indication Biosciences in the Statin+ platform for hypercholesterolemia, statin intolerance, and cardiovascular disease. It is described as a rosuvastatin-based combination that pairs rosuvastatin with an undisclosed complementary FDA-approved small molecule. Its intended pharmacology is lipid lowering driven by the established statin mechanism, principally inhibition of **3-hydroxy-3-methylglutaryl-coenzyme A reductase**, with the second component intended to improve tolerability and or therapeutic performance, although the partner molecule and its precise target biology have not been publicly disclosed. The company lists the program as preclinical.
- Brand names
- Rosova+
- Other names
- Rosova
02
Targets
HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)
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