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rosuvastatin + metformin
- Development stage
- Phase 3
- Lead developer
- BC World Pharm
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
BCWP_C003 is a fixed-dose combination oral drug consisting of rosuvastatin and metformin. It is being developed for the treatment of hyperlipidemia (anti-hyperlipidemia) and potentially for type 2 diabetes mellitus and dyslipidemias. The drug acts as both an AMPK agonist (via metformin) and an HMG-CoA reductase inhibitor (via rosuvastatin), targeting metabolic pathways to lower cholesterol levels and improve glycemic control. The developer is BC World Pharm, with involvement from Jeil Pharmaceutical and Yuhan Corp in its development pipeline[1][4][5][6]. Clinical trials have compared the pharmacokinetics of this combination product to co-administration of individual components[5].
- Brand names
- Rosumet
- Other names
- rosuvastatin calcium/metformin hydrochloride
02
Targets
PRKAB1 (AMPK β1)HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)
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