S-(N-hydroxy-N-bromophenylcarbamoyl)glutathione

S-(N-hydroxy-N-bromophenylcarbamoyl)glutathione is a synthetic small molecule derivative of glutathione, in which the glutathione moiety is conjugated to a N-hydroxy-N-bromophenylcarbamoyl group. It has been catalogued as an experimental compound and appears in pharmaceutical databases such as DrugBank and ZINC15. The compound is structurally related to other S-substituted glutathiones that have been studied as inhibitors of enzymes like glyoxalase I, an enzyme involved in detoxification pathways. However, there are no approved therapeutic indications or marketed products containing this molecule[1][3]. Its mechanism of action may involve acting as a competitive inhibitor or substrate mimic for enzymes that process glutathione conjugates.

Other names

L-gamma-glutamyl-S-[(S)-[(4-bromophenyl)(hydroxy)amino](hydroxy)methyl]-L-cysteinylglycine(2S)-2-Amino-5-[[(2R)-3-[(S)-(4-bromo-N-hydroxyanilino)-hydroxymethyl]sulfanyl-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acidS-(N-HYDROXY-N-BROMOPHENYLCARBAMOYL)GLUTATHIONEL-gamma-glutamyl-S-((S)-((4-bromophenyl)(hydroxy)amino)(hydroxy)methyl)-L-cysteinylglycine