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S-{3-[(4-anilinoquinazolin-6-yl)amino]-3-oxopropyl}-L-cysteine

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

S-{3-[(4-anilinoquinazolin-6-yl)amino]-3-oxopropyl}-L-cysteine is a synthetic small molecule derivative of 4-anilinoquinazoline. Quinazoline derivatives, including those with an anilino group at the 4-position and amino substitution at the 6-position, are well known as potent inhibitors of protein kinases such as the epidermal growth factor receptor (EGFR). Many compounds in this class have been developed and approved as anticancer drugs (e.g., gefitinib, erlotinib, afatinib). The specific compound here is structurally related to these kinase inhibitors and may act by inhibiting EGFR or other kinases. Some quinazoline derivatives have also shown antiviral activity against coronaviruses in preclinical studies[1][2][3][7].

02

Targets

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