Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
saffron extract + scutellaria baicalensis extract
- Development stage
- Unknown
- Lead developer
- Green Plants Extracts
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
**saffron extract + scutellaria baicalensis extract** is a combination of two standardized botanical extracts, *saffron* (*Crocus sativus*) and *scutellaria baicalensis* ("Huang-Qin"). This combination has demonstrated a **synergistic effect** in reducing symptoms of mild-to-moderate depression and anxiety. Saffron extract is known for its mood-regulating effects, primarily by modulating neurotransmitter systems like serotonin, norepinephrine, and dopamine and exerting anti-inflammatory effects. Scutellaria baicalensis extract contains bioactive flavonoids such as baicalin and baicalein, which increase brain dopamine levels, protect dopaminergic neurons, inhibit monoamine oxidase, enhance GABAergic activity, and provide anti-inflammatory and antioxidative benefits. The synergistic combination was clinically demonstrated to improve emotional well-being, reduce depression and anxiety scores, and was well-tolerated over a six-week supplementation period with minimal adverse effects. The specific commercial formulation studied was SAFFR’UP[1].
- Brand names
- SAFFR’UP
- Other names
- saffron and scutellaria extract combination
02
Targets
GABRR (GABA-A receptor subunit rho)MAOA (Monoamine oxidase A)SERT (Sodium-dependent serotonin transporter)BDNF (Brain-derived neurotrophic factor)DAT (Dopamine plasma membrane transport protein)GABA-B (Gamma-aminobutyric acid receptor type B)
Beyond the preview
Go deeper on saffron extract + scutellaria baicalensis extract.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on saffron extract + scutellaria baicalensis extract.