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salacia extract + citrus bioflavonoids + trivalent chromium
- Development stage
- Unknown
- Lead developer
- Mend Labs
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
A combination dietary supplement containing **Salacia chinensis extract**, **citrus bioflavonoids**, and **trivalent chromium** (often referenced as SEC) is clinically investigated for improvement of glucose control and metabolic health. **Salacia chinensis** includes polyphenolic compounds (salacinol, mangiferin, kotalanol) that inhibit *pancreatic lipase*, *aldose reductase*, and *alpha-glucosidase*, enzymes crucial for breaking down lipids and carbohydrates—thus reducing glucose absorption and fat digestion. **Citrus bioflavonoids** act as antioxidant and anti-inflammatory agents, potentially supporting glycemic and metabolic outcomes. **Trivalent chromium** is an essential micronutrient that enhances insulin receptor function, potentially aiding glucose uptake and insulin sensitivity. Clinical data show this triple combination reduces sweet cravings, glucose and insulin responses after an oral sucrose load, improves adiponectin, and may support kidney function. Primary indications are metabolic syndrome, glucose intolerance, obesity, and insulin resistance[1][5][7].
- Brand names
- Control Glucose
- Other names
- Salacia chinensis extract + citrus bioflavonoids + trivalent chromium
02
Targets
AR (Adrenergic receptors)PPARA (Peroxisome proliferator-activated receptor alpha)PNLIP (Pancreatic triacylglycerol lipase)AGTR1 (Angiotensin II Type-1 receptor)Sucrase-Isomaltase
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