Drug intelligence / Profile preview

salbutamol + beclometasone dipropionate

Development stage
Unknown
Lead developer
GSK
Modality
Small Molecules
Administration
Inhalation
01

Overview

Salbutamol + beclometasone dipropionate is a fixed-dose combination inhalation therapy containing salbutamol (a short-acting beta2-adrenergic receptor agonist, or SABA) and beclometasone dipropionate (an inhaled corticosteroid, or ICS). Salbutamol acts as a rapid-acting bronchodilator by relaxing airway smooth muscle, while beclometasone dipropionate provides potent anti-inflammatory effects in the lungs. This combination is indicated for the long-term management and prevention of symptoms associated with asthma and chronic obstructive pulmonary disease (COPD) in patients who require both bronchodilator and corticosteroid therapy. It is typically administered via a pressurized metered-dose inhaler (pMDI).

Brand names
Beclo-salBeclomolBeclosalButosolDerisoneSalbesoneVentideXaltideXaltide HFA
Other names
albuterol + beclomethasone dipropionatealbuterol sulfate + beclomethasone dipropionatesalbutamol + beclomethasone dipropionatesalbutamol and beclometasone dipropionatesalbutamol and beclomethasone dipropionatesalbutamol sulfate + beclometasone dipropionatesalbutamol sulfate + beclomethasone dipropionatesalbutamol sulphate + beclometasone dipropionatesalbutamol sulphate + beclomethasone dipropionate
02

Targets

MR (Mineralocorticoid receptor)GR (Glucocorticoid receptor)ADRB3 (β3)ADRB1 (β1)

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