salbutamol + terbutaline

Salbutamol + terbutaline is a combination of two short-acting beta-2 adrenergic receptor agonists, both used as bronchodilators for the symptomatic relief and prevention of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD). Both drugs act by selectively stimulating beta-2 adrenergic receptors in bronchial smooth muscle, leading to relaxation of airway muscles, bronchodilation, and improved airflow. They are also associated with increased heart rate and tremor due to their sympathomimetic effects. While each drug is commonly used individually or in multi-drug cough/cold formulations, there is limited evidence for a fixed-dose combination product containing only salbutamol and terbutaline; co-administration may increase the risk of cardiovascular side effects[1][3][4][5].