Drug intelligence / Profile preview

salicylic acid + ESP block

Development stage
Unknown
Lead developer
Hospital for Special Surgery
Modality
Small Molecules
Administration
Intrathecal, Perineural, Oral
01

Overview

The name "salicylic acid + ESP block" appears to be a misinterpretation of "SA + ESP" (Spinal Anesthesia + Erector Spinae Plane block), an anesthetic regimen being studied by the Hospital for Special Surgery (HSS). In the context of the Phase 3 clinical trial NCT05483400, researchers are comparing the efficacy of an Erector Spinae Plane (ESP) block combined with either spinal anesthesia (SA) or general anesthesia (GA) for patients undergoing lumbar decompression surgeries, such as those for lumbar disc herniation, lumbar disc disease, or lumbar radiculopathy. Salicylic acid is a salicylate nonsteroidal anti-inflammatory drug (NSAID) that provides analgesia by inhibiting cyclooxygenase enzymes. The ESP block is a regional anesthetic technique where local anesthetics (such as bupivacaine or mepivacaine) are injected into the fascial plane deep to the erector spinae muscle to provide multi-dermatomal sensory blockade, aiming to improve postoperative pain management and reduce opioid consumption.

Other names
SA + ESP blockSpinal Anesthesia + Erector Spinae Plane block
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

Beyond the preview

Go deeper on salicylic acid + ESP block.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on salicylic acid + ESP block.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call