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salicylic acid + niacinamide + zinc PCA + hyaluronic acid
- Development stage
- Unknown
- Lead developer
- The Derma Co
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
This combination is a topical dermatological formulation primarily used for the treatment of acne vulgaris and the management of oily, blemish-prone skin. Salicylic acid, a beta-hydroxy acid (BHA), acts as a keratolytic agent by penetrating sebum-filled pores to exfoliate dead skin cells and reduce comedone formation. Niacinamide (Vitamin B3) provides anti-inflammatory benefits, improves skin barrier function, and reduces post-inflammatory hyperpigmentation. Zinc PCA (Pyrrolidone Carboxylic Acid) serves as a sebum-regulating agent and possesses antimicrobial properties against *Cutibacterium acnes*. Hyaluronic acid is included as a humectant to counteract the potential drying effects of the active exfoliants, maintaining skin hydration and reducing irritation.
- Brand names
- The Derma Co 2% Salicylic Acid Face SerumBe Bodywise 2% Salicylic Acid Serum
- Other names
- salicylic acid + niacinamide + zinc PCA + hyaluronic acid
02
Targets
SRD5A (Steroid 5-alpha-reductase)
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