Drug intelligence / Profile preview

saline + glucose

Development stage
Unknown
Lead developer
Umeå University
Modality
Small Molecules
Administration
Intranasal
01

Overview

"Saline + glucose" is an inert placebo formulation used as a comparator in clinical trials, specifically in a Phase 2 study (NCT01883440) investigating a glucose oxidase nasal spray for the treatment of the common cold. The formulation consists of an isotonic saline solution supplemented with 5% glucose, delivered via a nasal spray. In the context of the trial led by Krister Tano at Umeå University, it serves as the control arm against an active treatment that utilizes glucose oxidase to enzymatically produce virucidal hydrogen peroxide. As a placebo, it lacks an active pharmaceutical ingredient and has no defined biological target or therapeutic effect.

Other names
isotonic saline with 5% glucose
02

Targets

Extracellular fluid compartment – NaClHK1/HK2 (Hexokinase 1 and Hexokinase 2)GLUT1 (Glucose transporter 1)SLC5A1 (Sodium Glucose Cotransporter 1)

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