saline solution (NaCl 0.9%)

Saline Solution (NaCl 0.9%) is a standard isotonic saline solution containing 0.9% sodium chloride. Administered intranasally, it acts mechanically to moisten the nasal mucosa, dilute thick mucus, and support mucociliary clearance, thereby helping to relieve nasal obstruction. Because it is a physiological solution, it does not target specific molecular receptors. In clinical development, it is frequently employed as a standard-of-care active comparator in trials evaluating investigational nasal therapies for conditions such as rhinitis and sinusitis.

Other names

isotonic salineisotonic saline solutionnormal salinenormal saline solutionphysiological salinephysiological saline solutionsalinesaline solutionsodium chloride 0.9%sodium chloride 0.9% solution