Drug intelligence / Profile preview

Sanhuang Yishen Capsule + semaglutide

Development stage
Preclinical
Lead developer
Novo Nordisk
Modality
Peptides
Administration
Oral, Subcutaneous
01

Overview

Sanhuang Yishen Capsule + semaglutide is a combination therapy consisting of the Traditional Chinese Medicine (TCM) Sanhuang Yishen Capsule and the glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide. Sanhuang Yishen Capsule is a Chinese patent medicine typically used to treat diabetic kidney disease (DKD) by tonifying the kidney, resolving blood stasis, and clearing heat. Semaglutide is a long-acting GLP-1 receptor agonist that enhances glucose-dependent insulin secretion and has demonstrated significant cardiovascular and renal protective benefits. This combination is primarily investigated in clinical research in China for its potential synergistic effects in managing type 2 diabetes mellitus complicated by diabetic nephropathy, aiming to improve glycemic control while reducing proteinuria and slowing the progression of renal impairment.

Other names
三黄益肾胶囊 + 司美格鲁肽Sanhuang Yishen Capsule and semaglutide
02

Targets

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