saquinavir + zidovudine + lamivudine

A **fixed dose combination** of three antiretroviral drugs: **saquinavir**, **zidovudine** (also known as AZT), and **lamivudine**. This combination is used as part of highly active antiretroviral therapy (HAART) for the treatment of human immunodeficiency virus (HIV) infection. - **Saquinavir** is an HIV protease inhibitor that blocks the HIV protease enzyme, which is necessary for viral replication and maturation. - **Zidovudine** and **lamivudine** are nucleoside reverse transcriptase inhibitors (NRTIs) that interrupt the activity of HIV reverse transcriptase, an enzyme required for the transcription of viral RNA into DNA. By combining these drugs, the regimen targets HIV replication at multiple stages, reducing the risk of resistance development and improving viral suppression. This combination is used in therapy regimens for patients with HIV, particularly in those naïve to protease inhibitors or requiring multi-drug regimens due to resistance[1].