Drug intelligence / Profile preview

scopolamine + atropine + edaravone + dexmedetomidine

Development stage
Unknown
Lead developer
GSK
Modality
Small Molecules
Administration
Intravenous, Transdermal, Ophthalmic, Intramuscular
01

Overview

This is a theoretical combination of four distinct drugs with different mechanisms of action and therapeutic uses. The combination includes: - **Scopolamine**: An anticholinergic muscarinic antagonist used for motion sickness, postoperative nausea and vomiting, and other conditions - **Atropine**: A related muscarinic antagonist used in ophthalmology and for bradycardia treatment - **Edaravone**: A free radical scavenger used for ALS and ischemic stroke - **Dexmedetomidine**: An α2 adrenergic receptor agonist used for sedation and analgesia There is no evidence that these four drugs are used together as an established combination product.

02

Targets

ADRA2A (α2A)HTR3A (5-hydroxytryptamine receptor 3A)mAChR (Muscarinic acetylcholine receptors)

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