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Drug intelligence / Profile preview
scutellaria baicalensis + coptis chinensis
- Development stage
- Preclinical
- Modality
- Small Molecules
- Administration
- Oral (as Decoction Or Extract)
01
Overview
The combination of scutellaria baicalensis (Chinese name: 黄芩, Huang Qin) and coptis chinensis (Chinese name: 黄连, Huang Lian) is a traditional Chinese herbal medicine pairing widely used for the treatment of various heat-related diseases. This herbal duo is known for its anti-inflammatory, antimicrobial, and hepatoprotective properties. The main active constituents include baicalin from scutellaria baicalensis and berberine from coptis chinensis. These compounds exhibit synergistic effects in modulating inflammation and microbial growth. The combination has been studied for its ability to alleviate acute alcoholic liver injury and other inflammatory conditions by enhancing the bioavailability of active ingredients through specific chemical interactions within the decoction[2][4][1]. Mechanistically, these herbs act on multiple biological targets including inflammatory pathways and microbial agents.
- Other names
- 黄芩 + 黄连Scutellaria baicalensis—Coptis chinensis pairSCPE (Scutellaria baicalensis‐Coptis chinensis paired extract)
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)Neuraminidase
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