Drug intelligence / Profile preview

scutellarin (Nanchang Hongyi Pharmaceutical)

Development stage
Unknown
Lead developer
Nanchang Hongyi Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Dengzhanhua Drop Pills (also known as Dengzhanhuasu Drop Pills) is an approved traditional Chinese medicine formulation containing scutellarin, a flavonoid glycoside extracted from the plant *Erigeron breviscapus* (Vant.) Hand.-Mazz. Developed and manufactured by companies such as Nanchang Hongyi Pharmaceutical, it is primarily indicated for the treatment of cardiovascular and cerebrovascular disorders, including ischemic stroke, cerebral infarction, and coronary heart disease. The drug's therapeutic effects are attributed to its ability to improve microcirculation, induce vasodilation, and inhibit platelet aggregation. Additionally, scutellarin demonstrates neuroprotective properties by mitigating oxidative stress and inflammatory responses in the brain, partly through the modulation of nitric oxide synthase and the inhibition of the NLRP3 inflammasome.

Brand names
Dengzhanhua Drop PillsDengzhanhuasu Diwan
Other names
灯盏花素滴丸Erigeron breviscapus extractDengzhanhuasuScutellarein-7-glucuronideScutellarein7-glucuronideScutellarein 7-glucuronide
02

Targets

iNOS (Nitric oxide synthase, inducible)NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)PKA (Cyclic amp-dependent protein kinase)

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