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seasonal influenza vaccine (Queen Saovabha Memorial Institute)
- Development stage
- Unknown
- Lead developer
- Queen Saovabha Memorial Institute
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intradermal, Intramuscular
01
Overview
The seasonal influenza vaccine (Queen Saovabha Memorial Institute) refers to a trivalent inactivated influenza vaccine (TIV) evaluated by the Queen Saovabha Memorial Institute for use in elderly populations. The specific research focused on dose-sparing strategies using intradermal administration compared to the standard intramuscular route. The vaccine contains hemagglutinin (HA) antigens from three seasonal influenza strains, typically including two Influenza A subtypes (H1N1 and H3N2) and one Influenza B lineage. By utilizing a two-site intradermal injection method, investigators aimed to achieve comparable immunogenicity to the standard 15 mcg intramuscular dose using lower antigen concentrations (6 mcg or 12 mcg total HA), potentially extending vaccine supply during shortages.
- Other names
- trivalent influenza vaccineTIVseasonal influenza vaccine
02
Targets
HA (Hemagglutinin)
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